We would like to present the abstract of our keynote speaker – Danny Porath – who is a professor in the institute of chemistry and center for nanotechnology of the Hebrew University. He is also serving as the Vice Dean for research of the Faculty of Science at the Hebrew University and he is the international ambassador of “The COINS 2018”!

DNA is primarily and with no doubt the most important biological molecule. Its double-strand recognition, as well as the ability to control its sequence and manipulate its structure open a multitude of ways to make it useful for molecular electronics. Step by step we improve the synthesized constructs and the measurement methods of single DNA-based molecules. In this lecture I will review the field and report on our progress in producing and measuring DNA-based building blocks towards the construction of DNA-based programmable circuits.

[1] “Direct measurement of electrical transport through DNA molecules”, Danny Porath, Alexey Bezryadin, Simon de Vries and Cees Dekker, Nature 403, 635 (2000).

[2] “Charge Transport in DNA-based Devices”, Danny Porath, Rosa Di Felice and Gianaurelio Cuniberti, Topics in Current Chemistry Vol. 237, pp. 183-228 Ed. Gary Shuster. Springer Verlag, 2004.

[3] “Direct Measurement of Electrical Transport Through Single DNA Molecules of Complex Sequence”, Hezy Cohen, Claude Nogues, Ron Naaman and Danny Porath, PNAS 102, 11589 (2005).

[4] “Long Monomolecular G4-DNA Nanowires”, Alexander Kotlyar, Nataly Borovok, Tatiana Molotsky, Hezy Cohen, Errez Shapir and Danny Porath, Advanced Materials 17, 1901 (2005).

[5] “Electrical characterization of self-assembled single- and double-stranded DNA monolayers using conductive AFM”, Hezy Cohen et al., Faraday Discussions 131, 367 (2006).

[6] “High-Resolution STM Imaging of Novel Poly(G)-Poly(C)DNA Molecules”, Errez Shapir, Hezy Cohen, Natalia Borovok, Alexander B. Kotlyar and Danny Porath, Phys. Chem. B 110, 4430 (2006).

[7] “Polarizability of G4-DNA Observed by Electrostatic Force Microscopy Measurements”, Hezy Cohen et al., Nano Letters 7(4), 981 (2007).

[8] “Electronic structure of single DNA molecules resolved by transverse scanning tunneling spectroscopy”, Errez Shapir et al., Nature Materials 7, 68 (2008).

[9] “A DNA sequence scanned”, Danny Porath, Nature Nanotechnology 4, 476 (2009).

[10] “The Electronic Structure of G4-DNA by Scanning Tunneling Spectroscopy”, Errez Shapir, et.al., J. Chem. C 114, 22079 (2010).

[11] “Energy gap reduction in DNA by complexation with metal ions”, Errez Shapir, G. Brancolini, Tatiana Molotsky, Alexander B. Kotlyar, Rosa Di Felice, and Danny Porath, Advanced Maerials 23, 4290 (2011).

[12] “Quasi 3D imaging of DNA-gold nanoparticle tetrahedral structures”, Avigail Stern, Dvir Rotem, Inna Popov and Danny Porath, Phys. Cond. Mat. 24, 164203 (2012).

[13] “Comparative electrostatic force microscopy of tetra- and intra-molecular G4-DNA”, Gideon I. Livshits, Jamal Ghabboun, Natalia Borovok, Alexander B. Kotlyar, Danny Porath, Advanced materials 26, 4981 (2014).

[14] “Long-range charge transport in single G4-DNA molecules”, Gideon I. Livshits et. al., Nature Nanotechnology 9, 1040 (2014).

[15] “Synthesis and Properties of Novel Silver containing DNA molecules”, Gennady Eidelshtein et. al., Advanced Materials 28, 4839 (2016).